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Modeling Assumptions for Single-Cell RNA-seq with scribe

This tutorial walks through a series of modeling and inference choices that scribe's Bayesian engine makes available for single-cell RNA-seq data, using the Jurkat Cells dataset from 10x Genomics (~3,200 cells, monoculture). Because there is only one cell type, the focus is entirely on the statistical models rather than biological heterogeneity.

Pre-computed outputs

This notebook requires a GPU to run. All outputs shown below were pre-computed and exported to static HTML. To re-run it yourself, clone the repository and execute the notebook with marimo edit docs/tutorials/jurkat_cells.py on a GPU-enabled machine.

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