Models

SCRIBE provides a comprehensive suite of probabilistic models for single-cell RNA sequencing data analysis:

• Base Models - Detailed documentation of SCRIBE’s core models:

  • Negative Binomial Dirichlet Multinomial (NBDM)

  • Zero-Inflated Negative Binomial (ZINB)

  • Negative Binomial with Variable Capture Probability (NBVCP)

  • Zero-Inflated Negative Binomial with Variable Capture Probability (ZINBVCP)

• Mixture Models - Extensions of base models for heterogeneous cell populations